Nanovex Biotechnologies, due to our knowledge and experience, offers a range of services related to bio-nanotechnology.

ENCAPSULATION – DRUG DELIVERY

Encapsulation of compounds into nanovesicles or PLGA nanoparticles is an interesting technique employed in medical, food, pharmaceutical and cosmetic industries. The encapsulation provides several benefits such as: protection of the compound, better bioavailability, masking of undesired tastes, stabilization of the compound encapsulated, controlled delivery, target delivery, etc.

Our technology and experience in the encapsulation of compounds allow us to develop different types of nanovesicles and PLGA nanoparticles in order to select the optimal system for desired application.

Nanovex Biotechnologies offers customized nanoencapsulation services and other related services such as delivery studies, surface modification and conjugation, among others.

NANOENCAPSULATION

From 600 Eur

Customized nanoencapsulation of compounds in nanovesicles or PLGA nanoparticles

Full characterization (Size, size distribution, Z-Potential and entrapment efficiency)

Free Advice

NANOENCAPSULATION OF PEPTIDES AND PROTEINS

From 800 Eur

Customized nanoencapsulation of proteins and peptides in nanovesicles or PLGA nanoparticles

Full characterization (Size, size distribution, Z-Potential and entrapment efficiency)


Free Advice

DELIVERY STUDIES

From 300 Eur

Delivery studies of the encapsulated compound, peptide or protein simulating different conditions

Different simulating conditions available: Gastric conditions, intestinal conditions, dermal and transdermal assys


Free Advice

In addition, nanovesicles and PLGA nanoparticles can be surfacely modified using proteins or other materials. Visit our BIOCONJUGATION section to get more info.

For further information about the encapsulation service, please contact us:

+34 985 98 00 98  |   info@nanovexbiotech.com

CHARACTERIZATION

The service focus on the characterization of nanomaterials (metallic nanoparticles, nanovesicles, etc.) as well as other systems (extracellular vesicles, natural colloids, etc.) ranged from 0.3 nm to 100 μm. In addition to the characterization, Nanovex offers personal advicing and technical assistance.

Our team has a broad experience in the characterization of diverse nanomaterials. In addition, our facilities are equipped with the latest characterization technology.

Our aim is to offer a fast and personalized service, including data processing and technical advice in order to improve the sample characteristics and to provide as information as possible to evaluate the nanomaterial.

ParameterAvailable techniques
SizeDynamic Light Scattering (DLS), Nanoparticle Track Analysis (NTA), Transmission Electron Microscopy (TEM) and High Resolution Transmission Electron Microscopy (HR-TEM)
Size distributionDynamic Light Scattering (DLS), Nanoparticle Track Analysis (NTA), Transmission Electron Microscopy (TEM) and High Resolution Transmission Electron Microscopy (HR-TEM)
Nanoparticle / Nanovesicle / EXOSOME concentrationNanoparticle Track Analysis (NTA)
Z-PotentialMixed Mode Measurement – Phase Analysis Light Scattering (M3-PALS)
MorphologyTransmission Electron Microscopy (TEM) and High Resolution Transmission Electron Microscopy (HR-TEM)
Entrapment efficiencyPurification (Dialysis, centrifugation and/or Size Exclusion Chromatography) and Determination (HPLC, GC, Spectroscopy, etc.)
Structural analysisFourier-Transform infrared spectroscopy
FluorescenceFluorometry
StabilityMultiple Light Scattering (MLS)

For more/further information about the characterization service, please contact us

+34 985 98 00 98  |   info@nanovexbiotech.com

BIOCONJUGATION

Nanovex Biotechnologies  has a team with a broad experience in the conjugation of antibodies and proteins using different molecules such as fluorochromes, electrochemical species or enzymes, including:

  • Biotine
  • Fluorescein
  • Ferrocene
  • HRP

In addition, we are specialized in nanomaterial surface modification using protein material. Some nanomaterials which could be modificated are:

  • Gold nanoparticles (GNP, AuNP)
  • Silver nanoparticles (AgNP)
  • Alloyed Gold@Silver nanoparticles
  • Magnetic nanoparticles
  • Quantum dots (QDs)
  • MWCNTs
  • Nanovesicles
  • PLGA nanoparticles

After surface modification the obtained product is subjected to several purification and characterization processes to get a high quality and purified surface modified product.

SURFACE CONJUGATION - OPTION 1

From 600 Eur

Passive adsorption / Covalent conjugation of proteins to metallic nanoparticles, nanovesicles or PLGA nanoparticles

Full characterization (Size, size distribution and Z-Potential)

Determination of the bounded protein by UV-VIS

Free Advice

SURFACE CONJUGATION - OPTION 2

From 800 Eur

Passive adsorption / Covalent conjugation of proteins to metallic nanoparticles, nanovesicles or PLGA nanoparticles

Full characterization (Size, size distribution and Z-Potential)


Determination of the bounded protein by ICP


Free Advice

BIOCONJUGATION

From 300 Eur

Conjugation of antibodies and other proteins

Different chemical markers: Biotine, fluorescein, ferrocene and HRP among others. 




Free Advice

For further information about the bioconjugation service, please contact us:

+34 985 98 00 98  |   info@nanovexbiotech.com