Description

PLGA series

Poly(lactic-co-glycolic acid) (PLGA) is one of the most successfully developed biodegradable polymers. PLGA is a biocompatible, biodegradable and safely administrable polymer approved by the US FDA (Food and Drug Administration) and EMA (European Medicines Agency).

Nanovex Biotechnologies provides plain polymeric biodegradable nanoparticles (Nps) based on poly(lactide-co-glycolide) (PLGA) acid terminated with a lactide/glycolide ratio of 50/50 and a molecular weight of 32000 Da. There are different types of PLGA nanoparticles  so that our clients can select the nanoparticle that best suits their needsnanoparticles. In addition,  these nanoparticles can be externally functionalized with different compounds (NH₂⁺, PEI, proteins,…)

PLGA nanoparticles are available in various sizes of 50, 100 and 200nm

• Our PLGA Standard nanoparticles can encapsulate both hydrophilic and lipophilic compounds. These nanoparticles are negative charged and they are available in different sizes (50, 100 or 200 nm)

• Our PLGA-FLUO  nanoparticles can encapsulate both hydrophilic and lipophilic compounds. These nanoparticles chan show different types of fluorescence (green, red or pH sensitive fluorescence) and they are available in different sizes (50, 100 or 200 nm)

• Our PLGA-PEI nanoparticles can encapsulate both hydrophilic and lipophilic compounds. These nanoparticles are positive charged due to the surface modification with PEI. PLGA-PEI nanoparticles are recommended for gene or drug delivery (intracellular delivery) and they are available in different sizes (100 or 200 nm)

• Our PLGA-PEG nanoparticles can encapsulate both hydrophilic and lipophilic compounds. These nanoparticles are surfacely modified with PEG and they are recommended for “in vivo” assays.  PLGA-PEG nanoparticles are available in different sizes (100 or 200 nm)

• Our PLGA-PEI-FLUO nanoparticles can encapsulate both hydrophilic and lipophilic compounds. These nanoparticles are positive charged due to the surface modification with PEI and they can show different types of fluorescence (green, red or pH sensitive fluorescence), they are recommended for gene or drug delivery (intracellular delivery) with fluorescence detection. PLGA-PEI-FLUO nanoparticles are available in different sizes (100 or 200 nm)

• Our PLGA-PEG-FLUO nanoparticles can encapsulate both hydrophilic and lipophilic compounds. These nanoparticles are surfacely modified with PEG and they can show different types of fluorescence (green, red or pH sensitive fluorescence), they are recommended for “in vivo” assays with fluorescence detection. PLGA-PEG-FLUO nanoparticles are available in different sizes (100 or 200 nm)

CUSTOMIZED ENCAPSULATION SERVICE

Moreover, Nanovex Biotechnologies offers a customized encapsulation service to fabricate specific PLGA nanoparticles suitable for drug delivery, targeted drug delivery, gene delivery, theranostics, modeled to the specific needs of the customers. In this service, we can encapsulate your desired compound (drugs, biocompounds, …) in our different PLGA nanoparticles in order to meet the customer requirements