- CUSTOM SERVICES CATALOGUE
ENCAPSULATION – DRUG DELIVERY
Encapsulation of compounds into nanovesicles or PLGA nanoparticles is an interesting technique employed in medical, food, pharmaceutical and cosmetic industries. The encapsulation provides several benefits such as: protection of the compound, better bioavailability, masking of undesired tastes, stabilization of the compound encapsulated, controlled delivery, target delivery, etc.
Our technology and experience in the encapsulation of compounds allow us to develop different types of nanovesicles and PLGA nanoparticles in order to select the optimal system for desired application.
Nanovex Biotechnologies offers customized nanoencapsulation services and other related services such as delivery studies, surface modification and conjugation, among others.
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NANOENCAPSULATION
From 600 Eur
Customized nanoencapsulation of compounds in nanovesicles or PLGA nanoparticles
Full characterization (Size, size distribution, Z-Potential and entrapment efficiency)
Free Advice
NANOENCAPSULATION OF PEPTIDES AND PROTEINS
From 800 Eur
Customized nanoencapsulation of proteins and peptides in nanovesicles or PLGA nanoparticles
Full characterization (Size, size distribution, Z-Potential and entrapment efficiency)
Free Advice
DELIVERY STUDIES
From 300 Eur
Delivery studies of the encapsulated compound, peptide or protein simulating different conditions
Different simulating conditions available: Gastric conditions, intestinal conditions, dermal and transdermal assys
Free Advice
In addition, nanovesicles and PLGA nanoparticles can be surfacely modified using proteins or other materials. Visit our BIOCONJUGATION section to get more info.
For further information about the encapsulation service, please contact us:
CHARACTERIZATION
The service focus on the characterization of nanomaterials (metallic nanoparticles, nanovesicles, etc.) as well as other systems (extracellular vesicles, natural colloids, etc.) ranged from 0.3 nm to 100 μm. In addition to the characterization, Nanovex offers personal advicing and technical assistance.
Our team has a broad experience in the characterization of diverse nanomaterials. In addition, our facilities are equipped with the latest characterization technology.
Our aim is to offer a fast and personalized service, including data processing and technical advice in order to improve the sample characteristics and to provide as information as possible to evaluate the nanomaterial.
Parameter | Available techniques |
---|---|
Size | Dynamic Light Scattering (DLS), Nanoparticle Track Analysis (NTA), Transmission Electron Microscopy (TEM) and High Resolution Transmission Electron Microscopy (HR-TEM) |
Size distribution | Dynamic Light Scattering (DLS), Nanoparticle Track Analysis (NTA), Transmission Electron Microscopy (TEM) and High Resolution Transmission Electron Microscopy (HR-TEM) |
Nanoparticle / Nanovesicle / EXOSOME concentration | Nanoparticle Track Analysis (NTA) |
Z-Potential | Mixed Mode Measurement – Phase Analysis Light Scattering (M3-PALS) |
Morphology | Transmission Electron Microscopy (TEM) and High Resolution Transmission Electron Microscopy (HR-TEM) |
Entrapment efficiency | Purification (Dialysis, centrifugation and/or Size Exclusion Chromatography) and Determination (HPLC, GC, Spectroscopy, etc.) |
Structural analysis | Fourier-Transform infrared spectroscopy |
Fluorescence | Fluorometry |
Stability | Multiple Light Scattering (MLS) |
For more/further information about the characterization service, please contact us
BIOCONJUGATION
Nanovex Biotechnologies has a team with a broad experience in the conjugation of antibodies and proteins using different molecules such as fluorochromes, electrochemical species or enzymes, including:
- Biotine
- Fluorescein
- Ferrocene
- HRP
In addition, we are specialized in nanomaterial surface modification using protein material. Some nanomaterials which could be modificated are:
- Gold nanoparticles (GNP, AuNP)
- Silver nanoparticles (AgNP)
- Alloyed Gold@Silver nanoparticles
- Magnetic nanoparticles
- Quantum dots (QDs)
- MWCNTs
- Nanovesicles
- PLGA nanoparticles
After surface modification the obtained product is subjected to several purification and characterization processes to get a high quality and purified surface modified product.
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Projects
SURFACE CONJUGATION - OPTION 1
From 600 Eur
Passive adsorption / Covalent conjugation of proteins to metallic nanoparticles, nanovesicles or PLGA nanoparticles
Full characterization (Size, size distribution and Z-Potential)
Determination of the bounded protein by UV-VIS
Free Advice
SURFACE CONJUGATION - OPTION 2
From 800 Eur
Passive adsorption / Covalent conjugation of proteins to metallic nanoparticles, nanovesicles or PLGA nanoparticles
Full characterization (Size, size distribution and Z-Potential)
Determination of the bounded protein by ICP
Free Advice
BIOCONJUGATION
From 300 Eur
Conjugation of antibodies and other proteins
Different chemical markers: Biotine, fluorescein, ferrocene and HRP among others.
Free Advice
For further information about the bioconjugation service, please contact us: